TixelJobs

AI Jobs Paying $300,000+ (2026)

AI positions paying $300,000 or more in base salary represent the pinnacle of the field. These roles include Distinguished Engineers, VP-level leaders, Principal Research Scientists, and key technical contributors at the world's most valuable AI organizations. Competition is fierce, but compensation reflects the transformative value these professionals deliver.

Last updated: May 13, 2026

323
Open positions
$349K+
Avg salary
9
Companies hiring

Latest AI Jobs Paying $300K+

View all jobs
P
Pump.co2mo ago

Account Executive

San Francisco, CA, US$330K - $510K/yrFull-time
#yc-s22#yc
C
Confido2mo ago

Staff ML / AI Engineer

New York, NY, US$300K - $350K/yrFull-time
#yc-s21#yc
P
Parallel Bio2w ago

Vice President of Technology

San Francisco, CA, US$300K - $350K/yrFull-time
#yc
OpenAI
OpenAINew1d ago

Head of Growth GSIs - Cognizant Infosys & Wipro

San Francisco$378K - $500K/yrFull-time
#ai-lab
OpenAI
OpenAI2d ago

Executive Transformation Program Lead, Embedded Experience

San Francisco$378K - $441K/yrFull-time
#ai-lab
N
Nebius5d ago

Principal, Business Development - Physical AI

REMOTE$300K - $350K/yrFull-time
OpenAI
OpenAI5d ago

ChatGPT For Work - Early Access Program

San Francisco$302K - $335K/yrFull-time
#ai-lab
OpenAI
OpenAI5d ago

Head of GTM Business Operations & Strategy, Safety & Security

San Francisco$347K - $405K/yrFull-time
#ai-lab
E
Earnin5d ago

Head of Machine Learning

Mountain View, US$477K - $583K/yrFull-time
OpenAI
OpenAI6d ago

Product Manager, Sensitive Deployments

San Francisco$347K - $385K/yrFull-time
#ai-lab
H
Harvey1w ago

Engineering Director, New Verticals

New York$320K - $360K/yrFull-time
#ai-lab
OpenAI
OpenAI1w ago

Ads Product Manager

San Francisco$441K - $515K/yrFull-time
#ai-lab
OpenAI
OpenAI1w ago

Partnerships Lead, Healthcare

San Francisco$333K - $370K/yrFull-time
#ai-lab
W
Writer1w ago

Strategic account executive (West)

San Francisco, CA$340K - $350K/yrFull-time
#ai-lab
OpenAI
OpenAI1w ago

Associate General Counsel, Executive Compensation & Benefits

San Francisco$347K - $385K/yrFull-time
#ai-lab
A
Arcinstitute1w ago

Director, Machine Learning, Alzheimer's Disease Initiative

Palo Alto, CA$380K - $420K/yrFull-time
OpenAI
OpenAI1w ago

Partner Manager, Cloud Service Provider Partnerships

San Francisco$333K - $370K/yrFull-time
#ai-lab
A
Arcinstitute1w ago

Director, Machine Learning, Virtual Cell Initiative

Palo Alto, CA$380K - $420K/yrFull-time
H
Harvey1w ago

Mid Market Sales Manager, NY

New York$320K - $340K/yrFull-time
#ai-lab
OpenAI
OpenAI1w ago

Private Equity Lead

New York City$335K - $350K/yrFull-time
#ai-lab

Frequently Asked Questions

Who earns $300K+ base in AI?

Distinguished and Principal Engineers at FAANG companies, Research Directors at frontier labs, VP/SVP of AI/ML at tech companies, and founding/early engineers at unicorn AI startups. Senior LLM Engineers earn $220K-$350K+ in base, while AI leadership total compensation averages approximately $380K. Senior NLP roles at top tech can reach up to $400K. These roles typically require 10+ years of deep experience or groundbreaking research contributions, and AI engineer roles have surged 143% year-over-year creating more paths to this level.

What total compensation do $300K+ base roles offer?

Roles with $300K+ base salary often have total compensation of $500K to $1.5M+ when including equity, bonuses, and signing packages. At companies like OpenAI, Anthropic, and Google DeepMind, top researcher and engineering compensation can exceed $2M annually. For context, the average AI Engineer total comp is $211K, so $300K+ base represents roughly the top 5-10% of the field. SF, NYC, and Boston carry 20-50% premiums that push more roles into this elite tier.

What specializations lead to $300K+ salaries?

The fastest paths to $300K+ include senior LLM engineering ($220K-$350K+ base), frontier research scientist roles, CUDA/GPU engineering ($180K-$350K+ with senior roles exceeding $400K total), AI safety leadership ($135K-$221K base with 45% growth since 2023), and AI executive positions. Technical leadership combining deep ML expertise with people management is particularly valued, as is expertise in large-scale model training and alignment research.

AI Job Insights for AI Jobs Paying $300K+

Salary Range (Yearly, USD)

$300K - $1000K

Median $330K from 274 listings with salary data

Top Companies Hiring

OpenAI (10)Harvey (2)Arcinstitute (2)Pump.co (1)Confido (1)Parallel Bio (1)

Based on recent listings shown on this page.

Common Roles

Account Executive (1)Staff ML / AI Engineer (1)Vice President of Technology (1)Head of Growth GSIs - Cognizant Infosys & Wipro (1)Executive Transformation Program Lead, Embedded Experience (1)Principal, Business Development - Physical AI (1)

Counts reflect recent listings, not total market size.

In-Demand Skills

Ai Lab (13)Yc (3)Yc S22 (1)Yc S21 (1)

Derived from tags on recent listings.

AI Jobs Paying $300K+ | TixelJobs — Jobs at AI Companies