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Machine Learning Engineer Jobs in San Diego, CA

Looking for machine learning engineer roles in San Diego, CA? Browse curated positions from companies in the San Diego area. These roles typically require expertise in PyTorch, TensorFlow, Python, distributed training, model serving. Every listing is reviewed for quality and relevance.

Last updated: October 2, 2026

44
Local positions
$196K+
Avg salary
15
Companies hiring

Latest Machine Learning Engineer Jobs in San Diego

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M
Murata• 5d ago

Senior Machine Learning Engineer

San Diego, CAFull-time
I
Ignite Digital• 1w ago

AI Engineer

San Diego, CAFull-time
I
ICW Group• 1w ago

Applied AI Engineer

San Diego, CAFull-time
E
Elementbiosciences• 1w ago

Senior Engineer, Machine Learning

San Diego - Headquarters$139K - $183K/yrFull-time
C
Cellanome• 2w ago

Machine Learning Engineer

San Diego or Foster City$160K - $215K/yrFull-time
S
Shield AI• 2w ago

Senior Engineer, AI Engineering (R5856)

San Diego, CaliforniaFull-time
#ai-lab
A
Altoslabs• 2w ago

Director / Senior Director, Machine Learning for Biology

San Diego, CA; San Francisco Bay Area, CA$297K - $381K/yrFull-time
S
Sonyinteractiveentertainmentglobal• 3w ago

AI Engineer

United States, San Diego, CAFull-time
A
Acadiapharmaceuticals• 0mo ago

Director, AI Engineering

Princeton, New Jersey, United States; San Diego, California, United States; South San Francisco, California, United StatesFull-time
A
Acadiapharmaceuticals• 1mo ago

Associate Director, AI/ML Engineering

Princeton, New Jersey, United States; San Diego, California, United States; South San Francisco, California, United StatesFull-time
A
Acadiapharmaceuticals• 1mo ago

Senior Manager, AI Engineering

Princeton, New Jersey, United States; San Diego, California, United States; South San Francisco, California, United StatesFull-time
P
PwC• 2mo ago

US Tech - AI Engineering Senior Associate

REMOTEFull-time
#remote
P
PwC• 2mo ago

US Tech - AI Engineering Manager

REMOTEFull-time
#remote
S
Sonyinteractiveentertainmentglobal• 2mo ago

Senior Software Engineer, Machine Learning Platform

United States, San Diego, CA$187K - $266K/yrFull-time
A
Acadiapharmaceuticals• 3mo ago

Manager, AI Engineering

Princeton, New Jersey, United States; San Diego, California, United States; South San Francisco, California, United StatesFull-time
H
Hmbl Tech• 3mo ago

AI Engineer

San DiegoFull-time
G
G2It• 3mo ago

Lead Software & AI Engineer

San Diego, California, United StatesFull-time

Frequently Asked Questions

How many machine learning engineer jobs are available in San Diego?

The number of machine learning engineer positions in San Diego varies with market demand. Check our listings for the most current openings — we add new curated roles daily from multiple sources.

What skills do San Diego employers look for in machine learning engineers?

Machine Learning Engineer roles in San Diego, CA typically require strong skills in PyTorch, TensorFlow, Python, distributed training, model serving. Senior positions may also require system design experience and team leadership ability.

AI Job Insights for San Diego

Salary Range (Yearly, USD)

$80K - $381K

Median $158K from 21 listings with salary data

Top Companies Hiring

Acadiapharmaceuticals (4)Sonyinteractiveentertainmentglobal (2)PwC (2)Pmat (1)Optum (1)Northrop Grumman (1)

Based on recent listings shown on this page.

Common Roles

AI Engineer (3)Machine Learning Engineer III (Op AI) - TS clearance - San Diego, CA (1)Senior AI/ML Engineer - Remote (1)Staff AI Engineer Software (1)Senior Machine Learning Engineer (1)Applied AI Engineer (1)

Counts reflect recent listings, not total market size.

In-Demand Skills

Remote (3)Ai Lab (1)

Derived from tags on recent listings.